Premium Industrial Grade SR-9009 Powder (Stenabolic) for Research Applications

Introduction to SR-9009 (Stenabolic) Industrial Grade Chemical

In the evolving landscape of biochemical research, SR-9009 (Stenabolic) has emerged as a compound of significant interest for scientific investigation. As a leading supplier of industrial grade chemicals, RealChemSupply.com provides high-purity SR-9009 powder specifically designed for research applications requiring consistent quality and reliable performance.¹

SR-9009, also known as Stenabolic, is a synthetic Rev-ErbA agonist widely used in research to study metabolic regulation, circadian rhythm, endurance enhancement, and fat oxidation.¹ This compound was developed by Professor Thomas Burris at The Scripps Research Institute and is recognized for its ability to modulate the Rev-ErbA receptor, a key regulator of circadian rhythm and metabolic processes.^1 2

For research institutions, laboratories, and industrial facilities requiring bulk quantities of this compound, our industrial grade SR-9009 powder offers the purity and consistency necessary for reliable experimental outcomes. With a purity exceeding 98%, our product meets the stringent requirements of advanced research applications.¹

Chemical Properties and Specifications

Our industrial grade SR-9009 powder is characterized by its exceptional purity and chemical stability. The compound is supplied as a white to tan solid powder with the following specifications:

• Chemical Name: Ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate³
• CAS Number: 1379686-30-2¹⁰
• Molecular Formula: C₂₀H₂⁴ClN₃O₄S³
• Molecular Weight: 437.9 g/mol¹⁰
• Purity: ≥98% (LC-MS verification)¹⁰
• Appearance: White to tan solid powder

The compound functions as a potent REV-ERBα agonist with IC50 values of 670 nM and 800 nM for REV-ERBα and REV-ERBβ respectively.⁵ This specific activity profile makes it valuable for researchers studying metabolic regulation and circadian rhythm mechanisms.

Research Applications and Mechanism of Action

SR-9009 operates as a synthetic Rev-ErbA agonist, activating Rev-Erb nuclear receptors that influence energy expenditure and mitochondrial biogenesis.¹ This mechanism of action has made it a valuable tool in several research areas:

Metabolic Regulation Studies

Research has demonstrated that SR-9009 significantly impacts metabolic processes. The compound binds to Rev-erba, a natural protein in the body that influences lipid and glucose metabolism in the liver, inflammatory responses, and fat-storing cells.⁴ This process allows SR-9009 to kick start metabolism, along with increasing muscle strength in experimental models.⁴

Studies have shown that SR-9009 can re-sync a dysfunctional metabolic clock, ensuring that food and excess fat are used as energy.⁴ This property has made it particularly valuable for research into metabolic syndrome and related conditions.

Circadian Rhythm Research

As a REV-ERB agonist, SR-9009 plays a crucial role in feedback regulation of the circadian rhythm since both Bmal1 and Clock genes are direct targets of the receptors.³ Current research has found that loss of the REV-ERB-alpha protein leads to altered circadian behavior, making SR-9009 a valuable tool for studying these mechanisms.³

The compound has been shown to inhibit the activity of the SCN clock, with reversible inhibition of circadian oscillations in SCN explants cultured from the Per2:luc reporter mouse.⁵ This makes it particularly useful for chronobiology research.

Endurance Enhancement Studies

In experimental models, SR-9009 has demonstrated the ability to enhance endurance and exercise capacity. The compound has been studied in mice and shown to increase running speed, decrease levels of obesity, and stimulate mitochondrial production, thus enhancing muscle mass and metabolism.³

These properties have led to its investigation as a potential tool for understanding exercise physiology and endurance mechanisms at the molecular level.

Quality Assurance and Industrial Standards

At RealChemSupply.com, we understand that research applications demand uncompromising quality and consistency. Our industrial grade SR-9009 powder undergoes rigorous testing and quality control procedures to ensure:

• Consistent purity levels exceeding 98%
• Accurate chemical composition verification
• Stability testing for various storage conditions
• Comprehensive documentation including Material Safety Data Sheets (MSDS)¹⁰
• Batch-to-batch consistency for reliable research outcomes

Our product is specifically formulated for industrial and research applications, ensuring that researchers receive a product that meets the demanding requirements of advanced scientific investigation.

Bulk Supply and Industrial Applications

For industrial and research facilities requiring substantial quantities of SR-9009, our bulk supply options provide several advantages:

• Cost-effective pricing for volume purchases
• Consistent quality across large batches
• Reliable supply chain management
• Customized packaging options to meet specific facility requirements
• Technical support for research applications

Our industrial grade SR-9009 powder is suitable for various research applications including pharmaceutical research, biochemical studies, metabolic research, and circadian rhythm investigations.

Storage and Handling Guidelines

Proper storage and handling of SR-9009 powder are essential to maintain its integrity and effectiveness. We recommend:

• Storage in a cool, dry place away from direct sunlight
• Temperature-controlled environments between 2-8°C for long-term storage
• Airtight containers to prevent moisture absorption
• Handling in appropriate laboratory settings with personal protective equipment
• Following all safety protocols outlined in the Material Safety Data Sheet

Compliance and Regulatory Information

It is important to note that SR-9009 is intended for research purposes only and should not be used for human consumption or veterinary use.⁵ All products supplied by RealChemSupply.com are for research use only, and we comply with all relevant regulations regarding the distribution of research chemicals.

Researchers and institutions are responsible for ensuring compliance with all applicable regulations in their jurisdiction regarding the purchase, storage, and use of SR-9009 for research purposes.

Ordering and Technical Support

To order industrial grade SR-9009 powder or to discuss your specific research requirements, please visit RealChemSupply.com. Our technical support team is available to assist with:

• Product specifications and technical information
• Bulk ordering options and pricing
• Shipping and logistics for industrial quantities
• Documentation and certification requirements
• Research application guidance

Conclusion

SR-9009 (Stenabolic) represents a valuable tool for researchers investigating metabolic regulation, circadian rhythm, and endurance enhancement. Our industrial grade SR-9009 powder provides the purity, consistency, and reliability necessary for advanced research applications.

As a trusted supplier of industrial grade chemicals, RealChemSupply.com is committed to supporting the research community with high-quality products and exceptional service. For more information about our SR-9009 powder or other research chemicals, please visit our website or contact our technical support team.

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